Functional cookies made from black rice for oxidative stress control in overage and obesity adolescents
Health problems in Indonesia generally occur because of the unhealthy lifestyles of adolescents or sedentary lifestyles. The most common cases are health problems, such as obesity and overweight. This study aimed to measure the effect of providing functional cookies on controlling oxidative stress in obese adolescents, determine the compliance of cookie consumption by subjects, and conduct consumer tests. The study used an experimental design conducted from August to September 2022 at SMP Negeri 7 Cirebon City. The participants were 24 adolescents aged 13-15 years. Data were collected using questionnaires and analyzed for malondialdehyde (MDA) and Superoxide Dismutase (SOD) levels in the blood serum. Data analysis was performed using the Mann-Whitney U test and Pearson correlation test at 95% CI. The results showed that the provision of functional cookies significantly (p<0,05) reduced serum malondialdehyde (MDA) levels in overweight and normal adolescents (p = 0,017). Superoxide dismutase (SOD) enzyme activity had no effect on overweight/obese and normal adolescents after providing functional cookies. In conclusion, providing functional cookies can reduce MDA levels in obese and normal adolescents (p = 0,017) but had no effect on SOD enzyme activity. The adherence to cookie consumption and consumer test results support its potential in controlling oxidative stress in adolescents.
Keywords : Adolescents, Cookies, MDA, Obesity, SOD
- Aleksandrova, K., Koelman, L., & Rodrigues, C. E. (2021). Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies. Redox Biology, 42, 101869. https://doi.org/10.1016/j.redox.2021.101869
- Amrynia, S. U., & Prameswari, G. N. (2022). Hubungan Pola Makan, Sedentary Lifestyle, dan Durasi Tidur dengan Kejadian Gizi Lebih Pada Remaja (Studi Kasus di SMA Negeri 1 Demak). Indonesian Journal of Public Health and Nutrition, 2(1), 112–121. https://doi.org/10.15294/ijphn.v2i1.52044
- Artadini, G. M., Simanungkalit, S. F., & Wahyuningsih, U. (2022). The Relationship Between Eating Habits, Social Media Exposure and Peers With Nutritional Status of Nutrition Students at UPN Veteran Jakarta. Jgk, 14(2), 317–329.
- Ávila-Escalante, M. L., Coop-Gamas, F., Cervantes-Rodríguez, M., Méndez-Iturbide, D., & Aranda-González, I. I. (2020). The effect of diet on oxidative stress and metabolic diseases—Clinically controlled trials. Journal of Food Biochemistry, 44(5), 1–16. https://doi.org/10.1111/jfbc.13191
- Azizah, Z. A. N. (2019). Pengaruh Kombinasi Ekstrak Etanol Bawang Dayak (Eleutherine bulbosa) dan Kayu Manis (Cinnamomum Burmanii) terhadap Kadar SOD-MDA Hepar Mencit Dislipidemia. UNIVERSITAS ISLAM NEGERI MAULANA MALIK IBRAHIM.
- Cherubini, A., Ruggiero, C., Polidori, M. C., & Mecocci, P. (2005). Potential markers of oxidative stress in stroke. Free Radical Biology and Medicine, 39(7), 841–852. https://doi.org/10.1016/j.freeradbiomed.2005.06.025
- Galanakis, C. M. (2021). Functionality of food components and emerging technologies. Foods, 10(1), 1–26. https://doi.org/10.3390/foods10010128
- Ghasemzadeh, A., Karbalaii, M. T., Jaafar, H. Z. E., & Rahmat, A. (2018). Phytochemical constituents, antioxidant activity, and antiproliferative properties of black, red, and brown rice bran. Chemistry Central Journal, 12(1), 1–13. https://doi.org/10.1186/s13065-018-0382-9
- Lidiawati, M., Lumongga, N., & Anto. (2020). Faktor yang Mempengaruhi Perilaku Makan pada Remaja Obesitas di SMA Kota Banda Aceh. Jurnal Aceh Mdedika, 4(1), 52–62. http://jurnal.abulyatama.ac.id/index.php/acehmedika
- Lupiana, M., Sutrio, S., & Indriyani, R. (2022). Hubungan Pola Makan Remaja Dengan Indeks Massa Tubuh Di Smp Advent Bandar Lampung. PREPOTIF : Jurnal Kesehatan Masyarakat, 6(2), 1135–1144. https://doi.org/10.31004/prepotif.v6i2.4376
- Muscolo, A., Mariateresa, O., Giulio, T., & Mariateresa, R. (2024). Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases. International Journal of Molecular Sciences, 25(6). https://doi.org/10.3390/ijms25063264
- Shao, Y., Hu, Z., Yu, Y., Mou, R., Zhu, Z., & Beta, T. (2018). Phenolic acids, anthocyanins, proanthocyanidins, antioxidant activity, minerals and their correlations in non-pigmented, red, and black rice. Food Chemistry, 239, 733–741. https://doi.org/10.1016/j.foodchem.2017.07.009
- Gropper, SS et al., 2009. Advance Nutrition and Human Metabolism.
- Irawan, R. 2013. Hubungan Obesitas Terhadap Kadar Malondialdehid (MDA) Plasma pada Mahasiswa Program Studi Pendidikan Dokter Uin Syarif Hidayatullah Jakarta.
- Intantri, H.Y. 2008. Hubungan Antara Aldosteron, Plasma Renin Activity (Pra) Dan Superoxide Dismutase (SOD) dengan Inflamasi (Hscrp) dan Resistensi Insulin (Homa Ir) pada Pria Dewasa dengan Obesitas Sentral.
- Montero, D et al., 2011. Etiology and Pathophysiology/Prevention: Endothelial Dysfunction, Inflammation, and Oxidative Stress Obese Children and Adolescent: Marker and Effect of Lifestyle Intervention.
- Nisa, K. 2017. Pengaruh Pemberian Ekstrak Etanol 70% Biji Rambutan (Nephelium Lappaceum L) Terhadap Kenaikan Kadar SOD dan Penurunan MDA Pankreas Mencit (Mus Musculus) yang Diinduksi Streptozotocin.
- Patil S, Kaur C. 2018. Review current trends in extrusion: development of functional foods and novel ingredients. Food Science and Technology Research. 24(1): 23-24.
- Riset Kesehatan Dasar (Riskesdas). 2018.
- Simbolon, et al., 2018. Pola Aktivitas Fisik
- Widyawati PS, Suteja AM, Suseno TIP, Monika P, Saputrajaya W, Liguori C. 2014. Pengaruh perbedaan warna pigmen beras organik terhadap aktivitas antioksidan. Agritech. 34(4): 399-406.
- Yanti et al., 2016. Perbedaan Kadar Superokside Dismutase pada Remaja dengan Dismenore Primer dan Tanpa Dismenore Primer. Jurnal Kesehatan Andalas.
- Yosika et al., 2020. Penurunan Malondialdehyde (MDA) Serum setelah Latihan Interval dan Continuous di Pagi Hari Pada Perempuan Obesitas.
- Zulfahmidah et al., 2021. Hubungan Obesitas dan Stress Oksidatif. UMI Medical Journal. Vol.6 Issue:1.


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