Supp. File(s): common.other
Literature Review: The effect of modification diet and antioxidant on inflammatory and oxidative stress concentration in obesity
Obesity is also associated with increased inflammation and oxidative stress. Mediterranean and dash diets, as well as antioxidants, can reduce inflammation and oxidative stress levels in obesity. This study aimed to determine the effects of dietary modifications and antioxidants on inflammatory and oxidative stress levels in obesity. This study was carried out using the literature review method using PubMed, Science Direct, and Google Scholar databases with the keywords Mediterranean Diet, DASH Diet, Antioxidant, Obesity, Inflammation, and Oxidative Stress. The inclusion criteria in this literature are articles published in the last 5 years (2018-2023) using RCT, in English, subjects >18 years old with obesity, interventions providing Mediterranean and dash diet, antioxidants derived from natural ingredients, and articles that can be accessed online. Articles were selected individually through a double process, considering the three main research quality criteria. This study showed that a modified diet and antioxidants can reduce inflammatory biomarkers and oxidative stress in obesity by suppressing NF-κB signaling and protecting against DNA damage. In conclusion, a modified diet and antioxidants can reduce inflammatory and oxidative stress in obesity.
Supplement Files
Keywords : Dash diet, Inflammation, Meddiet, Obesity, Oxidative stress
- Bae, J., Kim, N., Shin, Y., Kim, S.-Y., & Kim, Y.-J. (2020). Activity of catechins and their applications. Biomedical Dermatology, 4(1), 1–10. https://doi.org/10.1186/s41702-020-0057-8
- Benson, G., & Hayes, J. (2020). An update on the mediterranean, vegetarian, and DASH eating patterns in people with type 2 diabetes. Diabetes Spectrum, 33(2), 125–132. https://doi.org/10.2337/ds19-0073
- Bernatoniene, J., & Kopustinskiene, D. M. (2018). The role of catechins in cellular responses to oxidative stress. Molecules, 23(4), 1–11. https://doi.org/10.3390/molecules23040965
- Blüher, M. (2019). Obesity: Global epidemiology and pathogenesis. Nature Reviews Endocrinology, 15(5), 288–298. https://doi.org/10.1038/s41574-019-0176-8
- Bucciantini, M., Leri, M., Nardiello, P., Casamenti, F., & Stefani, M. (2021). Olive polyphenols: Antioxidant and anti-inflammatory properties. Antioxidants, 10(7). https://doi.org/10.3390/antiox10071044
- Castro-Barquero, S., Ruiz-León, A. M., Sierra-Pérez, M., Estruch, R., & Casas, R. (2020). Dietary strategies for metabolic syndrome: A comprehensive review. Nutrients, 12(10), 1–21. https://doi.org/10.3390/nu12102983
- Cazzola, R., & Rondanelli, M. (2020). N-Oleoyl-phosphatidyl-ethanolamine and epigallo catechin-3-gallate mitigate oxidative stress in overweight and class I obese people on a low-calorie diet. Journal of Medicinal Food, 23(3), 319–325. https://doi.org/10.1089/jmf.2019.0145
- Dewantari, N., & Sukraniti, D. (2020). Efek konseling germas terhadap implementasi germas dan indeks massa tubuh wanita dewasa di pusat kebugaran. AcTion: Aceh Nutrition Journal, 5(1), 62-70. http://dx.doi.org/10.30867/action.v5i1.209
- DiNicolantonio, J. J., Mehta, V., Onkaramurthy, N., & O’Keefe, J. H. (2018). Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity. Progress in Cardiovascular Diseases, 61(1), 3–9. https://doi.org/10.1016/j.pcad.2017.12.001
- Dominguez, L. J., Veronese, N., Di Bella, G., Cusumano, C., Parisi, A., Tagliaferri, F., Ciriminna, S., & Barbagallo, M. (2023). Mediterranean diet in the management and prevention of obesity. Experimental Gerontology, 174(February), 112121. https://doi.org/10.1016/j.exger.2023.112121
- Filippou, C. D., Tsioufis, C. P., Thomopoulos, C. G., Mihas, C. C., Dimitriadis, K. S., Sotiropoulou, L. I., ... & Tousoulis, D. M. (2020). Dietary approaches to stop hypertension (DASH) diet and blood pressure reduction in adults with and without hypertension: a systematic review and meta-analysis of randomized controlled trials. Advances in nutrition, 11(5), 1150-1160. https://doi.org/10.1093/advances/nmaa041
- Finicelli, M., Di Salle, A., Galderisi, U., & Peluso, G. (2022). The mediterranean diet: An update of the clinical trials. Nutrients, 14(14). https://doi.org/10.3390/nu14142956
- Fitrah S. W., & Suwondo, A. (2022). A literature review of effect of moringa oleifera leaf extract toward lipid profile level in hyperlipidemia patients. International Journal of Nursing and Health Services (IJNHS), 5(3), 294–303. https://doi.org/10.35654/ijnhs.v5i3.581
- Grzesik, M., Naparło, K., Bartosz, G., & Sadowska-Bartosz, I. (2018). Antioxidant properties of catechins: Comparison with other antioxidants. Food Chemistry, 241(August 2017), 480–492. https://doi.org/10.1016/j.foodchem.2017.08.117
- Jimenez-Lopez, C., Carpena, M., Lourenço-Lopes, C., Gallardo-Gomez, M., Lorenzo, J. M., Barba, F. J., ... & Simal-Gandara, J. (2020). Bioactive compounds and quality of extra virgin olive oil. Foods, 9(8), 1014. https://doi.org/10.3390/foods9081014
- Kemenkes RI. (2018). Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI, 53(9), 1689–1699.
- Kenđel, J. G., Mrakovcic-Sutic, I., Pavičić Žeželj, S., Šuša, B., Rahelić, D., & Klobučar Majanović, S. (2020). The efficacy of an energy-restricted anti-inflammatory diet for the management of obesity in younger adults. Nutrients, 12(11), 3583. https://doi.org/10.3390/nu12113583
- Kim, J. Y. (2021). Optimal diet strategies for weight loss and weight loss maintenance. Journal of Obesity and Metabolic Syndrome, 30(1), 20–31. https://doi.org/10.7570/JOMES20065
- Koelman, L., Egea, R. C., & Aleksandrova, K. (2022). Effects of dietary patterns on biomarkers of inflammation and immune responses: A systematic review and meta-analysis of randomized controlled trials. Advances in Nutrition, 13(1), 101–115. https://doi.org/10.1093/advances/nmab086
- Lin, X., & Li, H. (2021). Obesity: Epidemiology, pathophysiology, and therapeutics. Frontiers in Endocrinology, 12(September), 1–9. https://doi.org/10.3389/fendo.2021.706978
- Machado, A. M., da Silva, N. B. M., de Freitas, R. M. P., de Freitas, M. B. D., Chaves, J. B. P., Oliveira, L. L., Martino, H. S. D., & Alfenas, R. de C. G. (2020). Effects of yacon flour associated with an energy restricted diet on intestinal permeability, fecal short chain fatty acids, oxidative stress and inflammation markers levels in adults with obesity or overweight: A randomized, double blind, placebo controll. Archives of Endocrinology and Metabolism, 64(5), 597–607. https://doi.org/10.20945/2359-3997000000225
- Marin-Alejandre, B. A., Abete, I., Cantero, I., Monreal, J. I., Elorz, M., Herrero, J. I., Benito-Boillos, A., Quiroga, J., Martinez-Echeverria, A., Uriz-Otano, J. I., Huarte-Muniesa, M. P., Tur, J. A., Martinez, J. A., & Zulet, M. A. (2019). The metabolic and hepatic impact of two personalized dietary strategies in subjects with obesity and nonalcoholic fatty liver disease: The fatty liver in obesity (FLiO) randomized controlled trial. Nutrients, 11(10). https://doi.org/10.3390/nu11102543
- Mehta, N., Luthra, N. S., Corcos, D. M., & Fantuzzi, G. (2023). C-reactive protein as the biomarker of choice to monitor the effects of exercise on inflammation in Parkinson’s disease. Frontiers in Immunology, 14(May), 1–5. https://doi.org/10.3389/fimmu.2023.1178448
- Muñoz-García, R., Sánchez-Hidalgo, M., Montoya, T., Alcarranza, M., Ortega-Vidal, J., Altarejos, J., & Alarcón-de-la-Lastra, C. (2022). Effects of oleacein, a new epinutraceutical bioproduct from extra virgin olive oil, in LPS-activated murine immune cells. Pharmaceuticals, 15(11), 1–20. https://doi.org/10.3390/ph15111338
- Quetglas-Llabrés, M. M., Monserrat-Mesquida, M., Bouzas, C., Llompart, I., Mateos, D., Casares, M., Ugarriza, L., Martínez, J. A., Tur, J. A., & Sureda, A. (2023). Mediterranean diet improves plasma biomarkers related to oxidative stress and inflammatory process in patients with non-alcoholic fatty liver disease. Antioxidants, 12(4), 1–17. https://doi.org/10.3390/antiox12040833
- Raheem, A., Sultan, R., & Yasmeen, H. (2022). Epidemiology of obesity in asia: challenges and prevention. Advancements in Life Sciences, 9(2), 125–130.
- Rahmad, A. H., Fitri, Y., Suryana, S., Mulyani, N. S., Fajriansyah, F., & Abdul, H. (2020). Analysis of the relationship between nutritional influence with the obesity phenomenon among primary school students in Banda Aceh, Aceh Province, Indonesia. Macedonian Journal of Medical Sciences, 8(E), 267–270. https://doi.org/10.3889/oamjms.2020.3471
- Román, G. C., Jackson, R. E., Reis, J., Román, A. N., Toledo, J. B., & Toledo, E. (2019). Extra-virgin olive oil for potential prevention of Alzheimer disease. Revue Neurologique, 175(10), 705–723. https://doi.org/10.1016/j.neurol.2019.07.017
- Rooholahzadegan, F., Arefhosseini, S., Tutunchi, H., Badali, T., Khoshbaten, M., & Ebrahimi-Mameghani, M. (2023). The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial. Nutrition and Metabolism, 20(1), 1–14. https://doi.org/10.1186/s12986-023-00733-4
- Ruiz-García, I., Ortíz-Flores, R., Badía, R., García-Borrego, A., García-Fernández, M., Lara, E., Martín-Montañez, E., García-Serrano, S., Valdés, S., Gonzalo, M., Tapia-Guerrero, M. J., Fernández-García, J. C., Sánchez-García, A., Muñoz-Cobos, F., Calderón-Cid, M., El-Bekay, R., Covas, M. I., Rojo-Martínez, G., Olveira, G., … Bermúdez-Silva, F. J. (2023). Rich oleocanthal and oleacein extra virgin olive oil and inflammatory and antioxidant status in people with obesity and prediabetes. The APRIL study: A randomised, controlled crossover study. Clinical Nutrition, 42(8), 1389–1398. https://doi.org/10.1016/j.clnu.2023.06.027
- Schwingshackl, L., Morze, J., & Hoffmann, G. (2020). Mediterranean diet and health status: Active ingredients and pharmacological mechanisms. British Journal of Pharmacology, 177(6), 1241–1257. https://doi.org/10.1111/bph.14778
- Setyaningrum, A. A., Ardya, D., Sutoyo, R., & Raditya, A. D. (2021). Pengaruh diet tinggi sukrosa dan fruktosa terhadap obesitas pada hewan coba: Kajian pustaka. Amerta Nutrition, 173–179. https://doi.org/10.20473/amnt.v5i2.2021
- Sheng, Y., Sun, Y., Tang, Y., Yu, Y., Wang, J., Zheng, F., Li, Y., & Sun, Y. (2023). Catechins: Protective mechanism of antioxidant stress in atherosclerosis. Frontiers in Pharmacology, 14(March), 1–15. https://doi.org/10.3389/fphar.2023.1144878
- Soltani, S., Chitsazi, M. J., & Salehi-Abargouei, A. (2018). The effect of dietary approaches to stop hypertension (DASH) on serum inflammatory markers: A systematic review and meta-analysis of randomized trials. Clinical Nutrition, 37(2), 542–550. https://doi.org/10.1016/j.clnu.2017.02.018
- Suri, S., Kumar, V., Kumar, S., Goyal, A., Tanwar, B., Kaur, J., & Kaur, J. (2019). DASH dietary pattern: a treatment for non-communicable diseases. Current Hypertension Reviews, 16(2), 108–114. https://doi.org/10.2174/1573402115666191007144608
- Uchio, R., Kawasaki, K., Okuda-Hanafusa, C., Saji, R., Muroyama, K., Murosaki, S., Yamamoto, Y., & Hirose, Y. (2021). Curcuma longa extract improves serum inflammatory markers and mental health in healthy participants who are overweight: a randomized, double-blind, placebo-controlled trial. Nutrition Journal, 20(1), 1–14. https://doi.org/10.1186/s12937-021-00748-8
- Wang, Y., Qi, W., Song, G., Pang, S., Peng, Z., Li, Y., & Wang, P. (2020). High-fructose diet increases inflammatory cytokines and alters gut microbiota composition in rats. Mediators of Inflammation, 2020. https://doi.org/10.1155/2020/6672636
- Wickman, B. E., Enkhmaa, B., Ridberg, R., Romero, E., Cadeiras, M., Meyers, F., & Steinberg, F. (2021). Dietary management of heart failure: Dash diet and precision nutrition perspectives. Nutrients, 13(12), 1–24. https://doi.org/10.3390/nu13124424
- Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018). The immunomodulatory and anti-inflammatory role of polyphenols. Nutrients, 10(11), 1–23. https://doi.org/10.3390/nu10111618
- Yannakoulia, M., Poulimeneas, D., Mamalaki, E., & Anastasiou, C. A. (2019). Dietary modifications for weight loss and weight loss maintenance. Metabolism: Clinical and Experimental, 92, 153–162. https://doi.org/10.1016/j.metabol.2019.01.001
- Yilmaz, S., Calikoglu, E. O., & Kosan, Z. (2019). Prevalence of obesity among adolescents in Eastern Turkey: A cross-sectional study with a review of the local literature. Nigerian Journal of Clinical Practice, 22(8), 1070-1077. https://doi.org/10.4103/njcp.njcp_418_18
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.