Supp. File(s): Research Instrument
The inflammatory effects of diet, nutritional status, and severity of chronic kidney disease at Bogor City Hospital
Diet and nutritional status play an important role in chronic kidney disease (CKD). Pro-inflammatory foods are linked to a decline in kidney function, whereas the nutritional status of obesity is a risk factor for CKD. This study aimed to analyze the relationship between (DII), nutritional status, and CKD severity. This cross-sectional study was conducted between April and May 2023 at Bogor City Hospital. A total of 64 patients with CKD were selected using accidental sampling. Consumption data were collected from the SQ-FFQ, nutritional status was assessed using Body Mass Index (BMI), and disease severity was assessed using creatinine and estimated glomerular filtration rate (eGFR) levels. Data were analyzed using ANOVA, Kruskal-Wallis, Pearson, and Spearman correlation tests. Results: All subjects had positive DII scores, their nutritional status was mostly in the normal range (59,4%), and almost all subjects had CKD stage 5 (95,3%). No relationships were found between the DII score and creatinine level (p= 0,986) and eGFR (p= 0,359). There was also no relationship between nutritional status and creatinine (p= 0,985 ) and eGFR (0,442). In conclusion, a positive DII score indicated that all subjects consumed more pro-inflammatory foods. Actions are needed to get CKD patients with CKD who consume more anti-inflammatory foods.
Supplement Files
Keywords : Chronic kidney disease, dietary inflammatory index, nutritional status
- Alfonso, A. A., Mongan, A. E., & Memah, M. F. (2016). Gambaran kadar kreatinin serum pada pasien penyakit ginjal kronik stadium 5 non dialisis. EBiomedik, 4(1). https://doi.org/10.35790/ebm.v4i1.10862
- Almeida-de-Souza, J., Santos, R., Barros, R., Abreu, S., Moreira, C., Lopes, L., Mota, J., & Moreira, P. (2018). Dietary inflammatory index and inflammatory biomarkers in adolescents from LabMed physical activity study. European Journal of Clinical Nutrition, 72(5), 710–719. https://doi.org/10.1038/s41430-017-0013-x
- Câmara, N. O. S., Iseki, K., Kramer, H., Liu, Z.-H., & Sharma, K. (2017). Kidney disease and obesity: epidemiology, mechanisms and treatment. Nature Reviews Nephrology, 13(3), 181–190. https://doi.org/10.1038/nrneph.2016.191
- Ferdina, A. R., & Sembiring, W. S. R. G. (2022). Comparison of Obesity Indices in Predicting Diabetes Mellitus, Heart Disease, Chronic Kidney Disease, and High Blood Pressure among Adults in Kalimantan, Indonesia. Proceedings of the 3rd International Conference on Social Determinants of Health (ICSDH 2021), 100–105. https://doi.org/10.5220/0010759900003235
- Food Standards Australia New Zealand. (2023). Australian food composition database. Food Standards Australia New Zealand. https://www.foodstandards.gov.au/science-data/food-composition-databases
- Foreman, K. J., Marquez, N., Dolgert, A., Fukutaki, K., Fullman, N., McGaughey, M., Pletcher, M. A., Smith, A. E., Tang, K., & Yuan, C.-W. (2018). Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories. The Lancet, 392(10159), 2052–2090. http://dx.doi.org/10.1016/s0140-6736(18)31694-5
- Gounden, V., Bhatt, H., & Jialal, I. (2018). Renal function tests. StatPearls Publishing.
- Hill, N. R., Fatoba, S. T., Oke, J. L., Hirst, J. A., O’Callaghan, C. A., Lasserson, D. S., & Hobbs, F. D. R. (2016). Global prevalence of chronic kidney disease–a systematic review and meta-analysis. PloS One, 11(7), e0158765. https://doi.org/10.1371/journal.pone.0158765
- Inker, L. A., Eneanya, N. D., Coresh, J., Tighiouart, H., Wang, D., Sang, Y., Crews, D. C., Doria, A., Estrella, M. M., & Froissart, M. (2021). New creatinine-and cystatin C–based equations to estimate GFR without race. New England Journal of Medicine, 385(19), 1737–1749. https://doi.org/10.1056/NEJMoa2102953
- IRR. (2018). 11th report Of Indonesian renal registry 2018. Indonesian Renal Registry (IRR), 14–15.
- Kemenkes, R. I. (2018). RISKESDAS 2018.pdf. In Riset Kesehatan Dasar.
- Kemenkes, R. I. (2020). Tabel Komposisi Pangan Indonesia (TKPI). Direktorat Jenderal Kesehatan Masyarakat Direktorat Gizi Masyarakat. https://repository.kemkes.go.id/book/668
- Kizil, M., Tengilimoglu-Metin, M. M., Gumus, D., Sevim, S., Turkoglu, İ., & Mandiroglu, F. (2016). Dietary inflammatory index is associated with serum C-reactive protein and protein energy wasting in hemodialysis patients: A cross-sectional study. Nutrition Research and Practice, 10(4), 404–410. https://doi.org/10.4162/nrp.2016.10.4.404
- Kovesdy, C. P., Furth, S., Zoccali, C., & Committee, W. K. D. S. (2017). Obesity and kidney disease: hidden consequences of the epidemic. Physiology International, 104(1), 1–14. https://doi.org/10.1556/2060.104.2017.1.9
- Lakkis, J. I., & Weir, M. R. (2018). Obesity and kidney disease. Progress in Cardiovascular Diseases, 61(2), 157–167. https://doi.org/10.1016/j.pcad.2018.07.00
- Lv, J.-C., & Zhang, L.-X. (2019). Prevalence and disease burden of chronic kidney disease. Renal Fibrosis: Mechanisms and Therapies, 3–15. https://doi.org/10.1007/978-981-13-8871-2_1
- Mazidi, M., Shivappa, N., Wirth, M. D., Hebert, J. R., & Kengne, A. P. (2018). Greater Dietary Inflammatory Index score is associated with higher likelihood of chronic kidney disease. British Journal of Nutrition, 120(2), 204–209. https://doi.org/10.1017/S0007114518001071
- Nifalo, F. (2020). Hubungan indeks massa tubuh dengan penurunan fungsi ginjal. In Skripsi S1 - FK Usakti. Universitas Trisakti.
- Ricker, M. A., & Haas, W. C. (2017). Anti‐inflammatory diet in clinical practice: a review. Nutrition in Clinical Practice, 32(3), 318–325. https://doi.org/10.1177/0884533617700353
- Rouhani, M. H., Najafabadi, M. M., Surkan, P. J., Esmaillzadeh, A., Feizi, A., & Azadbakht, L. (2019). Dietary inflammatory index and its association with renal function and progression of chronic kidney disease. Clinical Nutrition ESPEN, 29, 237–241. https://doi.org/https://doi.org/10.1016/j.clnesp.2018.09.001
- Semira, J. G. (2023). Tingkat Inflamasi Diet dan Status Gizi Pasien Kanker Payudara di RSUD Kota Bogor. Skripsi S1 - Departemen Gizi Masyarakat Fakultas Ekologi Manusia IPB, Bogor.
- Shivappa, N., Steck, S. E., Hurley, T. G., Hussey, J. R., & Hébert, J. R. (2014). Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutrition, 17(8), 1689–1696.
- Suwitra, K., & Widiana, R. (2018). Status nutrisi pasien penyakit ginjal kronik yang menjalani hemodialisis reguler lebih dari 5 tahun di Rumah Sakit Umum Pusat Sanglah Denpasar. Medicina, 49(2). https://doi.org/10.15562/medicina.v49i2.228
- Thaha, M., & Widiana, I. G. R. (2019). The role of inflammation in chronic kidney disease. Indonesian Journal of Kidney and Hypertension, 2(3), 4–13.
- U.S. Department of Agriculture. (2024). Food Data Central. U.S. Department of Agriculture. https://fdc.nal.usda.gov/
- Umar, H. B. (n.d.). Dietary Inflammatory Index dan Hubungannya dengan Kolesterol LDL pada Wanita Usia Subur (WUS) Etnik Minangkabau. Universitas Indonesia.
- Webster, A. C., Nagler, E. V, Morton, R. L., & Masson, P. (2017). Chronic kidney disease. The Lancet, 389(10075), 1238–1252. http://dx.doi.org/10.1016/%0AS0140-6736(16)32064-5
- Yuda, H. T., Lestari, I. A., & Nugroho, F. A. (2021). Gambaran Usia dan Kepatuhan Diet Pada Pasien Gagal Ginjal Kronik di Ruang Hemodialisa RSUD dr. Soedirman Kebumen. Prosiding University Research Colloquium, 389–393.


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