Association between body composition and fasting blood glucose in patients with type 2 diabetes

Nazhif Gifari* -  Nutrition and Dietetic Study Program of Universitas Esa Unggul, Jakarta, Indonesia
Rachmanida Nuzrina -  Nutrition and Dietetic Study Program of Universitas Esa Unggul, Jakarta, Indonesia
Mury Kuswari -  Nutrition Study Program of Universitas Esa Unggul, Jakarta, Indonesia
Laras Sitoayu -  Nutrition and Dietetic Study Program of Universitas Esa Unggul, Jakarta, Indonesia
DOI : 10.30867/action.v10i2.2555

Type 2 Diabetes Mellitus (T2DM) has become a significant public health issue in Asia, with significantly increasing prevalence rates in recent decades, especially affecting blood glucose levels in patients with this type of diabetes. This study aimed to examine the correlation between body composition and fasting blood glucose levels in subjects with diabetes mellitus type 2.  The observational research used a cross-sectional design that included a sample of 68 subjects, conducted between August and May 2024 at the RSUP Fatmawati Hospital in Jakarta.  Data were analyzed using the chi-square test for bivariate analysis, and analysis of variance was used to compare the variables. Body composition was measured using body impedance analysis (BIA), physical activity levels were measured using the International Physical Activity Questionnaire Short Form (IPAQ-SF), and fasting blood glucose was measured using Accu-Chek Instant Strips. Dietary and beverage consumption habits, familial health history, smoking habits, sleep duration, and physical activity level were assessed using a structured questionnaire. The results showed a positive relationship between nutritional status, percent body fat, and waist circumference, with a negative correlation between muscle mass and fasting blood sugar levels. In conclusion, nutritional status, percent body fat, waist circumference, and muscle mass were associated  with  fasting blood glucose levels.

Keywords : Body composition, Fasting blood glucose, Type 2 diabetes

  1. Albers, J. D., Meertens, R. M., Savelberg, H. H. C. M., Köhler, S., Wesselius, A., Schram, M. T., Stehouwer, C. D. A., De Galan, B. E., Van Greevenbroek, M. M. J., Van Der Kallen, C. J. H., Eussen, S. J. P. M., Bosma, H., Schaper, N. C., & Koster, A. (2023). Both short and long sleep durations are associated with type 2 diabetes, independent from traditional lifestyle risk factors—The Maastricht Study. Sleep Health, 9(5), 733–741. https://doi.org/10.1016/j.sleh.2023.06.009
  2. Angeles-Agdeppa, I. (2020). Food and Nutrient Intake of Filipinos with Diabetes. Journal of Food and Nutrition Research, 8(6), 258–267. https://doi.org/10.12691/jfnr-8-6-3
  3. Argyropoulou, D., Geladas, N. D., Nomikos, T., & Paschalis, V. (2022). Exercise and Nutrition Strategies for Combating Sarcopenia and Type 2 Diabetes Mellitus in Older Adults. Journal of Functional Morphology and Kinesiology, 7(2), 48. https://doi.org/10.3390/jfmk7020048
  4. Bulgakova, S. V., Treneva, E. V., Kurmaev, D. P., Pervyshin, N. A., Kosareva, O. V., Sharonova, L. A., & Dolgikh, Y. A. (2023). Assessment of muscle mass and bone density in elderly patients with type 2 diabetes mellitus depending on the level of glycated hemoglobin. Science and Innovations in Medicine, 8(2), 96–102. https://doi.org/10.35693/2500-1388-2023-8-2-96-102
  5. Buss, V. H., Varnfield, M., Harris, M., & Barr, M. (2021). Validation of a lifestyle-based risk score for type 2 diabetes mellitus in Australian adults. Preventive Medicine Reports, 24, 101647. https://doi.org/10.1016/j.pmedr.2021.101647
  6. Buyinza, R., Nsamba, J., Muyingo, A., Matovu, N., Nabirye, G., Kantengwa, A., Akandunda, S., Sseguya, W., & Mathews, E. (2023). Body composition of type 2 diabetes patients in Uganda: A case-control study. Journal of Public Health in Africa, 14(1), 6. https://doi.org/10.4081/jphia.2023.2249
  7. Chen, Y., Ma, J., Lu, D., & Fang, Y. (2022). The risk factors of type 2 diabetes in hypertensive subjects. Frontiers in Endocrinology, 13, 901614. https://doi.org/10.3389/fendo.2022.901614
  8. Collins, G. S., Mallett, S., Omar, O., & Yu, L.-M. (2011). Developing risk prediction models for type 2 diabetes: A systematic review of methodology and reporting. BMC Medicine, 9(1), 103. https://doi.org/10.1186/1741-7015-9-103
  9. Duan, M.-J., Dekker, L. H., Carrero, J.-J., & Navis, G. (2022). Lifestyle patterns and incident type 2 diabetes in the Dutch lifelines cohort study. Preventive Medicine Reports, 30, 102012. https://doi.org/10.1016/j.pmedr.2022.102012
  10. Halvorsen, R. E., Elvestad, M., Molin, M., & Aune, D. (2021). Fruit and vegetable consumption and the risk of type 2 diabetes: A systematic review and dose–response meta-analysis of prospective studies. BMJ Nutrition, Prevention & Health, 4(2), 519–531. https://doi.org/10.1136/bmjnph-2020-000218
  11. Hodge, A. M., Karim, M. N., Hébert, J. R., Shivappa, N., & De Courten, B. (2021). Association between Diet Quality Indices and Incidence of Type 2 Diabetes in the Melbourne Collaborative Cohort Study. Nutrients, 13(11), 4162. https://doi.org/10.3390/nu13114162
  12. Hong, S., Park, J. H., Han, K., Lee, C. B., Kim, D. S., & Yu, S. H. (2022). Association Between Obesity and Cardiovascular Disease in Elderly Patients With Diabetes: A Retrospective Cohort Study. The Journal of Clinical Endocrinology & Metabolism, 107(2), e515–e527. https://doi.org/10.1210/clinem/dgab714
  13. Isfaizah, I., Murti, B., & Indarto, D. (2021). Path analysis on the effects of diets and lifestyle modifications in blood glucose control in patients with type5 2 diabetes mellitus. 10(01).
  14. Jabbar, J. A., Al Masri, A. H., Oweidat, F. A., Al Ahmad, M. M., Ali, O. B., Oweidat, Z. A., & Sreedharan, J. (2023). Family history of diabetes, hypertension, obesity and cardiovascular diseases in relation to self health-care. International Journal Of Community Medicine And Public Health, 10(3), 919–923. https://doi.org/10.18203/2394-6040.ijcmph20230601
  15. Kemenkes RI. (2018). Laporan Riset Kesehatan (RISKESDAS). Kemenkes RI. https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/1/Laporan%20Riskesdas%202018%20Nasional.pdf
  16. Kemenkes RI. (2023). Indonesian Health Survey. https://repository.badankebijakan.kemkes.go.id/id/eprint/5539/1/LAPORAN%20SKI%202023%20DALAM%20ANGKA_FINAL.pdf
  17. Kheriji, N., Boukhalfa, W., Mahjoub, F., Hechmi, M., Dakhlaoui, T., Mrad, M., Hadj Salah Bahlous, A., Ben Amor, N., Jamoussi, H., & Kefi, R. (2022). The Role of Dietary Intake in Type 2 Diabetes Mellitus: Importance of Macro and Micronutrients in Glucose Homeostasis. Nutrients, 14(10), 2132. https://doi.org/10.3390/nu14102132
  18. Kim, H. J., Lee, H.-W., Kang, M.-K., Leem, G. H., Kim, M.-H., & Song, T.-J. (2024). Association of Body Composition Changes with the Development of Diabetes Mellitus: A Nation-Wide Population Study. Diabetes & Metabolism Journal, 48(6), 1093–1104. https://doi.org/10.4093/dmj.2023.0243
  19. Mahboob Alam, T., Iqbal, M. A., Ali, Y., Wahab, A., Ijaz, S., Imtiaz Baig, T., Hussain, A., Malik, M. A., Raza, M. M., Ibrar, S., & Abbas, Z. (2019). A model for early prediction of diabetes. Informatics in Medicine Unlocked, 16, 100204. https://doi.org/10.1016/j.imu.2019.100204
  20. Maulina, N., Sawitri, H., Zakiyya, N., & Syifa, S. (2023). Diabetes Melitus Tipe 2 dan Hipertensi sebagai Faktor Risiko PJK pada Lansia. Jurnal Ilmiah Manusia Dan Kesehatan, 6(1), 29–36. https://doi.org/10.31850/makes.v6i1.1894
  21. Meng, C., Zhao, D., & Ye, X.-H. (2023). Association of body composition with bone mineral density and fractures in Chinese male type 2 diabetes mellitus. Medicine, 102(14), e33400. https://doi.org/10.1097/MD.0000000000033400
  22. Metsämarttila, E., Rodilla, E., Jokelainen, J., Herrala, S., Leppäluoto, J., Keinänen-Kiukaanniemi, S., & Herzig, K.-H. (2018). Effect of physical activity on pulse wave velocity in elderly subjects with normal glucose, prediabetes or Type 2 Diabetes. Scientific Reports, 8(1), 8045. https://doi.org/10.1038/s41598-018-25755-4
  23. Noviyanti, R. D., Dyah Kusudaryati, D. P., Visi Asmara, A.-N., & Hatifah, D. K. (2023). Correlation between Nutritional Status and Fasting Blood Glucose Levels in the Elderly: An Investigative Study. Genius Journal, 4(2), 334–339. https://doi.org/10.56359/gj.v4i2.307
  24. Pitoy, F. F., Mandias, R. J., & Senduk, A. F. S. (2024). Perilaku Merokok dan Kadar Gula Darah Penderita Diabetes Melitus. Nutrix Journal, 8(2), 171. https://doi.org/10.37771/nj.v8i2.1129
  25. Ranganathan, R. S., K, E. V., R, S., & Manimozhian, N. (2022). High Fasting Blood Sugar and Increased Waist Circumference as Risk Factors for Diabetic Retinopathy in Type 2 Diabetes Patients Older than 45 Years. Cureus. https://doi.org/10.7759/cureus.28291
  26. Sari, M. I., Sari, N., Darlan, D. M., & Prasetya, R. J. (2018). Cigarette Smoking and Hyperglycaemia in Diabetic Patients. Open Access Macedonian Journal of Medical Sciences, 6(4), 634–637. https://doi.org/10.3889/oamjms.2018.140
  27. Sbrignadello, S., Göbl, C., & Tura, A. (2022). Bioelectrical Impedance Analysis for the Assessment of Body Composition in Sarcopenia and Type 2 Diabetes. Nutrients, 14(9), 1864. https://doi.org/10.3390/nu14091864
  28. Sri Hari, Ty., Sree Sudha, T., Varghese, A. M., Krishna Sasanka, K. S. B. S., & Thangaraju, P. (2021). A study of risk factors and complications in elderly hypertensive subjects. Journal of Family Medicine and Primary Care, 10(6), 2230–2234. https://doi.org/10.4103/jfmpc.jfmpc_1959_20
  29. Sun, Z., Hu, Y., Yu, C., Guo, Y., Pang, Y., Sun, D., Pei, P., Yang, L., Chen, Y., Du, H., Jin, J., Burgess, S., Hacker, A., Chen, J., Chen, Z., Lv, J., & Li, L. (2022). Low-risk Lifestyle and Health Factors and Risk of Mortality and Vascular Complications in Chinese Patients With Diabetes. The Journal of Clinical Endocrinology & Metabolism, 107(9), e3919–e3928. https://doi.org/10.1210/clinem/dgac264
  30. Teo, P. S., Van Dam, R. M., Whitton, C., Tan, L. W. L., & Forde, C. G. (2021). Consumption of Foods With Higher Energy Intake Rates is Associated With Greater Energy Intake, Adiposity, and Cardiovascular Risk Factors in Adults. The Journal of Nutrition, 151(2), 370–378. https://doi.org/10.1093/jn/nxaa344
  31. Wardani, E. M., & Nugroho, R. F. (2023). The Correlation Lifestyle with the Incidence of Diabetes Mellitus Type 2. Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 12(3), 119–123. https://doi.org/10.14710/dmj.v12i3.37822
  32. Wong, J. C., O’Neill, S., Beck, B. R., Forwood, M. R., & Khoo, S. K. (2021). Comparison of obesity and metabolic syndrome prevalence using fat mass index, body mass index and percentage body fat. PLOS ONE, 16(1), e0245436. https://doi.org/10.1371/journal.pone.0245436
  33. Yamamoto, Y., Nagai, Y., Kawanabe, S., Hishida, Y., Hiraki, K., Sone, M., & Tanaka, Y. (2021). Effects of resistance training using elastic bands on muscle strength with or without a leucine supplement for 48 weeks in elderly patients with type 2 diabetes. Endocrine Journal, 68(3), 291–298. https://doi.org/10.1507/endocrj.EJ20-0550
  34. Zhang, L., Yang, H., & Yang, P. (2022). The Correlation between Type 2 Diabetes Mellitus and Cardiovascular Disease Risk Factors in the Elderly. Applied Bionics and Biomechanics, 2022, 1–7. https://doi.org/10.1155/2022/4154426
  35. Zhao, X., Song, B., Yao, T., Fan, H., Liu, T., Gao, G., Wang, K., Lu, W., & Liu, C. (2024). Waist circumference glucose, a novel and effective predictor of type 2 diabetes: A prospective cohort study. Frontiers in Endocrinology, 15, 1427785. https://doi.org/10.3389/fendo.2024.1427785
  36. Zin, C. A. J. C. M., Mohamed, W. M. I. W., Khan, N. A. K., & Ishak, W. R. W. (2022). Effects of Fruit and Vegetable Polyphenols on the Glycemic Control and Metabolic Parameters in Type 2 Diabetes Mellitus: A Review. Preventive Nutrition and Food Science, 27(3), 257–264. https://doi.org/10.3746/pnf.2022.27.3.257

Open Access Copyright (c) 2025 Nazhif Gifari, Rachmanida Nuzrina, Mury Kuswari, Laras Sitoayu
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