Determinants of diabetes mellitus among adults aged ≥40 years: A case-control study in Banda Aceh
Diabetes mellitus is characterized by hyperglycemia and remains a growing global public health concern, including in Aceh Province, Indonesia. Several determinants have been associated with its occurrence, including age, obesity, physical inactivity, smoking, and family history. This study aimed to investigate the association between obesity, physical activity, smoking habits, family history, and diabetes mellitus. A case–control study was conducted among 46 participants, consisting of 23 patients with diabetes mellitus and 23 non-diabetic controls who underwent laboratory examinations at the Clinical Pathology Laboratory of Dr. Zainoel Abidin Regional General Hospital in Banda Aceh. Primary data were collected through interviews and structured questionnaires, and secondary data were obtained from medical records between January and August 2023. Data were analyzed using univariate analysis, chi-square tests, and multivariate logistic regression. The prevalence of diabetes mellitus was 5.9% in women and 5.2% in men. Obesity was significantly associated with diabetes mellitus (p < 0.001), with an odds ratio of 23.02. In contrast, physical activity, smoking status, and family history of diabetes showed no significant association with diabetes mellitus (p > 0.05). In conclusion, obesity is a major risk factor for diabetes mellitus. Regular monitoring and control of the body mass index are essential strategies for maintaining an ideal body weight and reducing the risk of diabetes mellitus.
Keywords : Diabetes mellitus, obesity, case control study, risk factors, Indonesia
- Agustia, D., Marpaung, S. S. M., & Lubis, D. A. (2025). Effects of cinnamon extract on blood sugar levels of type 2 diabetes mellitus patients: Randomized controlled trial (RCT). AcTion: Aceh Nutrition Journal, 10(2), 237–244. https://doi.org/10.30867/action.v10i2.2261
- Akmal, A., Agustina, S., Husna, C., & Syarif, H. (2025). Determinan kejadian neuropati perifer pada pasien diabetes melitus tipe 2. Journal of Healthcare Technology and Medicine, 11(2), 1–7. https://doi.org/10.33143/jhtm.v11i2.5328
- Al Rahmad, A. H. (2021). Several risk factors of obesity among female school teachers and relevance to non-communicable diseases during the COVID-19 pandemic. Amerta Nutrition, 5(1), 31–40. https://doi.org/10.20473/amnt.v5i1.2021.31-40
- Alkharis, V. Z., Asiandi, Purwandari, R. D., & Supriyadi. (2025). Design and development of the DiabestFriend Android application for type 2 diabetes self-care management. MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan, 23(3), 213–219. https://doi.org/10.30595/medisains.v23i3.24043
- Anggraeni, S., & Fauziah, E. (2020). Determinan pemanfaatan Posbindu PTM di Desa Uwie wilayah kerja Puskesmas Muara Uya Kabupaten Tabalong. Promotif: Jurnal Kesehatan Masyarakat, 10(2), 138–144. https://doi.org/10.56338/pjkm.v10i2.1368
- Antoni, A., Aa, A., Hadi, A. J., & Nur, N. H. (2025). The impact of spirituality on blood glucose control among patients with type 2 diabetes mellitus in Padangsidimpuan. AcTion: Aceh Nutrition Journal, 10(3), 801–809. https://doi.org/10.30867/action.v10i3.2715
- Arania, R., Triwahyuni, T., Esfandiari, F., & Nugraha, F. R. (2021). Hubungan antara usia, jenis kelamin, dan tingkat pendidikan dengan kejadian diabetes mellitus di Klinik Mardi Waluyo Lampung Tengah. Jurnal Medika Malahayati, 5(3), 146–153. https://doi.org/10.33024/jmm.v5i3.4200
- Arbie, F. Y., Nawai, F., Febry, A. B., Harikedua, V. T., & Legi, N. N. (2025). Factors associated with central obesity among patients with non-communicable disease in urban areas of Gorontalo. AcTion: Aceh Nutrition Journal, 10(3), 712–719. https://doi.org/10.30867/action.v10i3.2259
- Chandrasekaran, P., & Weiskirchen, R. (2024). The role of obesity in type 2 diabetes mellitus—An overview. International Journal of Molecular Sciences, 25(3), Article 1882. https://doi.org/10.3390/ijms25031882
- Dinas Kesehatan. (2019). Profile kesehatan aceh 2019. Dinas Kesehatan Pemerintah Aceh.
- Direktorat Pencegahan dan Pengendalian Penyakit. (2019). Buku pedoman manajemen penyakit tidak menular. (P2PTM) Pencegahan dan Pengendalian Penyakit Tidak Menular.
- Gifari, N., Nuzrina, R., Kuswari, M., & Sitoayu, L. (2025). Association between body composition and fasting blood glucose in patients with type 2 diabetes. AcTion: Aceh Nutrition Journal, 10(2), 485–493. https://doi.org/10.30867/action.v10i2.2555
- Hafizi, A., Hasbie, N. F., Febriyani, A., & Kurniati, M. (2024). Hubungan antara usia, jenis kelamin dan indeks massa tubuh dengan kejadian diabetes mellitus tipe 2 di Rumah Sakit Pertamina Bintang Amin Husada. Jurnal Medika Malahayati, 8(4), 900–907. https://doi.org/10.33024/jmm.v8i4.17069
- Handayani, L. T., Kurniawan, H., Jumanto, J., Hidayat, H., Fatahillah, D., & Ascarya, F. (2023). Program latihan CERDIK dalam mendeteksi penyakit tidak menular (PTM). Jurnal Pengabdian Teknologi Informasi dan Kesehatan (DIANKES), 1(2), 76–84. https://doi.org/10.47134/diankes.v1i2.15
- Hariawan, H., Tidore, M., & Greeny Z, R. (2020). Perilaku pencegahan penyakit tidak menular pada remaja Ambon. Molucca Medica, 13(2), 16–24.
- Huriyati, E., Ratrikaningtyas, P. D., Projosasmito, S. R., & Farmawati, A. (2019). Kader hidup sehat dalam upaya promotif penyakit degeneratif. Journal of Community Empowerment for Health, 2(1), 36–43. https://doi.org/10.22146/jcoemph.41292
- International Diabetes Federation. (2021). IDF diabetes atlas (10th ed.). IDF Diabetes Atlas
- Jumadewi, A., Lizam, T. C., & Fathimi. (2023). Prevalensi dan determinan kejadian penyakit tidak menular di Laboratorium Patologi Klinik RSUD dr. Zainoel Abidin. Journal of Healthcare Technology and Medicine, 9(2), 885–898.
- Jumadewi, A., Rahmayanti, R., Fajarna, F., & Emmi, W. (2022). Kadar kreatinin serum pasien diabetes mellitus tipe 2 pada kelompok usia 40 tahun ke atas. Jurnal SAGO Gizi dan Kesehatan, 4(1), 52–57. https://doi.org/10.30867/gikes.v4i1.1060
- Kemenkes RI. (2019). Penyakit menular masih jadi perhatian pemerintah. Kemenkes RI. https://www.kemkes.go.id/index.php
- Kementerian Kesehatan Republik Indonesia. (2020). Penyakit tidak menular kini ancam usia muda. Kementerian Kesehatan RI
- Kumalasari, I. D., Musthofa, S. B., & Jati, S. P. (2023). Determinan perilaku self-care hipertensi pada usia dewasa di Asia Tenggara: Literature review. Media Publikasi Promosi Kesehatan Indonesia, 6(3), 410–415. https://doi.org/10.56338/mppki.v6i3.3212
- Nasrulsyah, C., Ichwansyah, F., Hermansyah, H., Abdullah, A., & Zahara, M. (2022). Pengaruh kebugaran, IMT dan umur terhadap risiko diabetes melitus pada pegawai negeri sipil. AcTion: Aceh Nutrition Journal, 7(2), 205–213. https://doi.org/10.30867/action.v7i2.891
- Nilson, E. A. F., Gianicchi, B., Ferrari, G., & Rezende, L. F. M. (2022). The projected burden of non-communicable diseases attributable to overweight in Brazil from 2021 to 2030. Scientific Reports, 12(1), Article 22345. https://doi.org/10.1038/s41598-022-26739-1
- Olfert, M. D., Barr, M. L., Charlier, C. M., Famodu, O. A., Zhou, W., Mathews, A. E., Byrd-Bredbenner, C., & Colby, S. E. (2018). Self-reported vs. measured height, weight, and BMI in young adults. International Journal of Environmental Research and Public Health, 15(10), Article 2216. https://doi.org/10.3390/ijerph15102216
- Patnaik, L., Panigrahi, S. K., Sahoo, A. K., Mishra, D., Muduli, A. K., & Beura, S. (2022). Effectiveness of mobile application for promotion of physical activity among newly diagnosed patients of type II diabetes: A randomized controlled trial. International Journal of Preventive Medicine, 13, Article 44. https://doi.org/10.4103/ijpvm.IJPVM_531_20
- Prasetyani, D., & Apriani, E. (2017). Karakteristik pasien diabetes melitus tipe II di puskesmas cilacap tengah 1 dan 2. Prosiding STIKES AL Irsyad Al Islamiyah Cilacap, 2011, 42-49.
- Puspaningtyas, D. E., Sari, P. M., Styaningrum, S. D., Sucipto, A., Rahmawati, D. M., & Lestari, G. P. (2024). Optimizing healthy snacks for diabetics: Study of fiber and starch digestibility of glucomannan-modified growol cookies. AcTion: Aceh Nutrition Journal, 9(1), 182–193. https://doi.org/10.30867/action.v9i1.1514
- Rahajeng, E. (2020). Penguatan Posbindu PTM dalam menurunkan prevalensi faktor risiko penyakit tidak menular utama. Badan Litbangkes.
- Rahman, F. A., Roekmantara, T., & Romadhona, N. (2022). Pengaruh obesitas terhadap kejadian penyakit jantung koroner pada populasi dewasa. Bandung Conference Series: Medical Science, 2(1), 1002–1008. https://doi.org/10.29313/bcsms.v2i1.1979
- Rahmatulloh, W., Ristiyorini, I., Kusumaningsih, W. S., Ainni, A. N., & Zakhroh, S. A. (2025). Patient adherence and diabetes distress on glycemic outcomes: A cross-sectional study. MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan, 23(1), 1–4. https://doi.org/10.30595/medisains.v23i1.23773
- Riskesdas. (2018). Hasil Utama RISKESDAS 2018. Badan Penelitian dan Pengembangan Kesehatan. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf
- Rosdah, A. A., Natasha, A., Fertilita, S., & Usman, D. (2025). Temporal changes in blood glucose levels and organ histopathology in alloxan-induced diabetic rats. MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan, 23(2), 94–99. https://doi.org/10.30595/medisains.v23i2.27022
- Ruze, R., Liu, T., Zou, X., Song, J., Chen, Y., Xu, R., Yin, X., & Xu, Q. (2023). Obesity and type 2 diabetes mellitus: Connections in epidemiology, pathogenesis, and treatments. Frontiers in Endocrinology, 14, Article 1161521. https://doi.org/10.3389/fendo.2023.1161521
- Saidah, S., Hafnidar, H., Rani, A., & Mawardi, M. (2023). Determinan faktor yang berhubungan dengan penyakit tidak menular pada jemaah haji Provinsi Aceh. Sehat Rakyat: Jurnal Kesehatan Masyarakat, 2(1), 99–108. https://doi.org/10.54259/sehatrakyat.v2i1.1424
- Sovia, S., Damayantie, N., & Insani, N. (2020). Determinan faktor prediabetes di Kota Jambi tahun 2019. Jurnal Ilmiah Universitas Batanghari Jambi, 20(3), 983–989. https://doi.org/10.33087/jiubj.v20i3.1088
- Sutrisna, E., Sari, Y., Pohan, K., Fitria, N., Mauliza, R., & Suriani. (2025). Effect of Benson relaxation therapy combined with medical nutrition therapy on blood sugar levels in patients with type 2 diabetes mellitus. AcTion: Aceh Nutrition Journal, 10(3), 783–789. https://doi.org/10.30867/action.v10i3.2697
- Tomic, D., Shaw, J. E., & Magliano, D. J. (2022). The burden and risks of emerging complications of diabetes mellitus. Nature Reviews Endocrinology, 18(9), 525–539. https://doi.org/10.1038/s41574-022-00690-7
- Yusnanda, F., Rochadi, R. K., & Maas, L. T. (2018). Pengaruh kebiasaan makan terhadap kejadian diabetes mellitus pada pra lansia di BLUD RSU Meuraxa Kota Banda Aceh. Jurnal Muara Sains, Teknologi, Kedokteran Dan Ilmu Kesehatan, 1(2), 153–158. https://doi.org/10.24912/jmstkik.v1i2.1043
- Wungow, L., Berhimpong, M., & Telew, A. (2021). Tingkat aktivitas fisik mahasiswa program studi ilmu kesehatan masyarakat Universitas Negeri Manado saat masa pandemi COVID-19. Jurnal Kesehatan Masyarakat UNIMA, 2(3), 22–27. https://doi.org/10.53682/ejkmu.vi.1732
- Yameny, A. A. (2024). Diabetes mellitus overview 2024. Journal of Bioscience and Applied Research, 10(3), 641–645. https://doi.org/10.21608/jbaar.2024.382794
- Pakpahan, H. A., Rahardjo, T. B., Kridawati, A., & Handajani, Y. S. (2024). Analisis Determinan Kejadian Hipertensi pada Lansia di Urban Jakarta. Jurnal Ilmu Kesehatan Masyarakat, 13(01), 78-87. https://doi.org/10.33221/jikm.v13i01.2566
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