Soy-Ipoghurt as an antidiabetic on hiperglicemic animal modelling Rattus norvegicus

I Putu Dedy Arjita -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
Dhika Juliana Sukmana* -  D3 Teknologi Laboratorium Medis, Politeknik Medica Farma Husada Mataram, Kota Mataram, Indonesia
Hardani Hardani -  D3 Farmasi, Politeknik Medica Farma Husada Mataram, Kota Mataram, Indonesia
Diani Sri Hidayati -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
I Putu Bayu Agus Saputra -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
DOI : 10.30867/action.v8i2.909

Treatment of Diabetes Mellitus (DM) is generally through optimizing a balanced diet. Soybeans and sweet potatoes have good antioxidants and can be developed as healthy foods for people with diabetes. Soybeans and sweet potatoes are processed into Soy-yoghurt. This study aims to determine the potential of soy yogurt as an antidiabetic in experimental animals, Rattus norvegicus induced by hyperglycemia, using Streptozotocin. This study used a experiment design with a total of 40 experimental animals. The research was conducted at the Medica Farma Husada Polytechnic Laboratory, Mataram, in 2022. The experimental animals that Streptozotocin (STZ) induced were then given Soy-yogurt orally at 3 ml and 3.5 ml doses. Experimental animals' Fasting Blood Glucose (FBG) levels were measured weekly using a Glucometer, while body weight (BW) was measured every three days. The results obtained were then analyzed statistically using the ANOVA test. The test results showed that there was a significant difference in blood sugar levels (p<0,05) in fasting given soy but no difference in BW (p>0,05). This study concludes that the provision of soybeans can affect the level of FBG  of the experimental animals but does not affect the BW of the experimental animals.

Keywords : Soy-yoghurt, Diabetes Mellitus, Streptozotocin, Blood glucose, Body Weight

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Open Access Copyright (c) 2023 I Putu Dedy Arjita, Dhika Juliana Sukmana, Hardani, Diani Sri Hidayati, I Putu Bayu Agus Saputra
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AcTion: Aceh Nutrition Journal
Published by: Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health.
Soekarno-Hatta Street, No. 168. Health Polytechnic of Aceh, Aceh Besar, 23352. Telp/Fax: 0651 46126 / 0651 46121.
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