Soy-Ipoghurt as an antidiabetic on hiperglicemic animal modelling Rattus norvegicus

I Putu Dedy Arjita -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
Dhika Juliana Sukmana* -  D3 Teknologi Laboratorium Medis, Politeknik Medica Farma Husada Mataram, Kota Mataram, Indonesia
Hardani Hardani -  D3 Farmasi, Politeknik Medica Farma Husada Mataram, Kota Mataram, Indonesia
Diani Sri Hidayati -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
I Putu Bayu Agus Saputra -  Fakultas Kedokteran, Universitas Islam Al-Azhar, Kota Mataram, Indonesia
DOI : 10.30867/action.v8i2.909

Supp. File(s): Data Analysis common.other common.other common.other common.other common.other

Treatment of Diabetes Mellitus (DM) is generally through optimizing a balanced diet. Soybeans and sweet potatoes have good antioxidants and can be developed as healthy foods for people with diabetes. Soybeans and sweet potatoes are processed into Soy-yoghurt. This study aims to determine the potential of soy yogurt as an antidiabetic in experimental animals, Rattus norvegicus induced by hyperglycemia, using Streptozotocin. This study used a experiment design with a total of 40 experimental animals. The research was conducted at the Medica Farma Husada Polytechnic Laboratory, Mataram, in 2022. The experimental animals that Streptozotocin (STZ) induced were then given Soy-yogurt orally at 3 ml and 3.5 ml doses. Experimental animals' Fasting Blood Glucose (FBG) levels were measured weekly using a Glucometer, while body weight (BW) was measured every three days. The results obtained were then analyzed statistically using the ANOVA test. The test results showed that there was a significant difference in blood sugar levels (p<0,05) in fasting given soy but no difference in BW (p>0,05). This study concludes that the provision of soybeans can affect the level of FBG  of the experimental animals but does not affect the BW of the experimental animals.

Supplement Files

Keywords : Soy-yoghurt, Diabetes Mellitus, Streptozotocin, Blood glucose, Body Weight

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Open Access Copyright (c) 2023 I Putu Dedy Arjita, Dhika Juliana Sukmana, Hardani, Diani Sri Hidayati, I Putu Bayu Agus Saputra
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AcTion: Aceh Nutrition Journal
Published by: Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health.
Soekarno-Hatta Street, No. 168. Health Polytechnic of Aceh, Aceh Besar, 23352. Telp/Fax: 0651 46126 / 0651 46121.
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