Effects of fiber and resistant starch in "Mangpis" cookies on changes in blood lipid profile in obese patients obesity

Masdayani Junita Napitupulu -  Instalasi Gizi RSUD Prof DR W.Z Johannes Kupang and Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
Ahmad Syauqy* -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
Nyoman Suci Widyastiti -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
Diana Nur Afifah -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
Etika Ratna Noer -  Instalasi Gizi RSUD Prof DR W.Z Johannes Kupang, Indonesia
DOI : 10.30867/action.v9i1.1269

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Abnormal lipid profiles can cause obesity-associated heart diseases. Increased total cholesterol, Low-Density Lipoprotein (LDL), triglyceride (TG), and High-Density Lipoprotein (HDL) levels are indicators of obesity. This study aimed to identify the dietary fiber and resistant starch in mangpis cookies and analyze the effects of mangpis cookies on reducing lipid profiles. This study used a pre-test and post-test  design to measure lipid profiles before and after eating mangpis. Mangpis cookies were prepared without wheat flour and replaced with 50% Bruguiera gymnorhiza mangrove flour and 50% banana flour. This experiment was conducted on 16 obese subjects. The sampling technique used was purposive. A decrease in the lipid profile was observed based on the results of blood tests before and after the consumption of mangpis cookies. The effect of the consumption of mangpis cookies on reducing lipid profiles was assessed using the Paired T-test and Wilcoxon test. The analysis results of the food fiber content and resistant starch contained in the mangpis cookies were 7,86 ± 004 and 6,65 ± 0,01 with p-value TG (p=0,001 and HDL (p=0,01). In conclusion, mangpis cookies were identified to contain 17,8% dietary fiber and 15% resistant starch, which could influence the lipid profile, especially TG levels.

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Keywords : Fiber, Starch resistant, Mangpis, Lipid Profile

  1. Abutair, A. S., Naser, I. A., & Hamed, A. T. (2016). Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial). Nutrition Journal, 15(1), 1–7. https://doi.org/10.1186/s12937-016-0207-4
  2. Adel Mehraban, M. S., Tabatabaei-Malazy, O., Rahimi, R., Daniali, M., Khashayar, P., & Larijani, B. (2021). Targeting dyslipidemia by herbal medicines: A systematic review of meta-analyses. Journal of Ethnopharmacology, 280(May), 1–33. https://doi.org/10.1016/j.jep.2021.114407
  3. Afifah, D. N., Sari, L. N. I., Sari, D. R., Probosari, E., Wijayanti, H. S., & Anjani, G. (2020). Analisis Kandungan Zat Gizi, Pati Resisten, Indeks Glikemik, Beban Glikemik dan Daya Terima Cookies Tepung Pisang Kepok (Musa paradisiaca) Termodifikasi Enzimatis dan Tepung Kacang Hijau (Vigna radiate). Jurnal Aplikasi Teknologi Pangan, 9(3), 101–107. https://doi.org/10.17728/jatp.8148
  4. Afzal, M. F., Khalid, W., Akram, S., Khalid, M. A., Zubair, M., Kauser, S., Abdelsamea Mohamedahmed, K., Aziz, A., & Anusha Siddiqui, S. (2022). Bioactive profile and functional food applications of banana in food sectors and health: a review. International Journal of Food Properties, 25(1), 2286–2300. https://doi.org/10.1080/10942912.2022.2130940
  5. Agung, L. R. (2021). Pengaruh Daun Salam (Syzygium polyanthum) Terhadap Kadar Trigliserida Dan Kolesterol Total Darah Pada Penderita Dislipidemia. Jurnal Ilmiah Kesehatan Sandi Husada, 10(2), 408–412. https://doi.org/10.35816/jiskh.v10i2.617
  6. Agustin, F., Febriyatna, A., Damayati, R. P., Hermawan, H., Faiziah, N., Santoso, R. D., & Wulandari, R. D. (2019). Effect of Unripe Berlin Banana Flour on Lipid Profile of Dyslipidemia Rats. Majalah Kedokteran Bandung, 51(2), 70–74. https://doi.org/10.15395/mkb.v51n2.1630
  7. Amalia, R., Pramono, A., Nur, D., Ratna, E., & Cahyo, A. (2022). Mangrove fruit (Bruguiera gymnorhiza) increases circulating GLP-1 and PYY , modulates lipid pro fi les , and reduces systemic in fl ammation by improving SCFA levels in obese wistar rats. Heliyon, 8(September), 1–10. https://doi.org/10.1016/j.heliyon.2022.e10887
  8. Andini, A. N., & Ardiaria, M. (2016). Pengaruh Pemberian Kombinasi Minyak Rami Dengan Minyak Wijen Terhadap Kadar Trigliserida Pada Tikus Sprague Dawley Dislipidemia. Journal of Nutrition College, 5(4), 555–564. https://doi.org/https:10.14710/jnc.v5i4.16472.
  9. Badan Pengawasan Obat dan Makanan, R. I. (2016). Peraturan Kepala Badan Pengawas Obat dan Makanan Republik Indonesia Tentang Pengawasan Klaim Pada Label dan Iklan Pangan Olahan (Vol. 3, Issue 1). https://doi.org/https://standarpangan.pom.go.id/dokumen/peraturan/2016/PerKa_BPOM_No_13_Tahun_2016_tentang_Klaim_pada_Label_dan_Iklan_Pangan_Olahan.pdf
  10. Bojarczuk, A., Skąpska, S., Mousavi Khaneghah, A., & Marszałek, K. (2022). Health benefits of resistant starch: A review of the literature. Journal of Functional Foods, 93(January), 1–11. https://doi.org/10.1016/j.jff.2022.105094
  11. Brahm, A., & Hegele, R. A. (2013). Hypertriglyceridemia. Nutrients, 5(3), 981–1001. https://doi.org/10.3390/nu5030981
  12. Budiyanto, F., Alhomaidi, E. A., Mohammed, A. E., Ghandourah, M. A., Alorfi, H. S., Bawakid, N. O., & Alarif, W. M. (2022). Exploring the Mangrove Fruit: From the Phytochemicals to Functional Food Development and the Current Progress in the Middle East. Marine Drugs, 20(5), 1–55. https://doi.org/10.3390/md20050303
  13. Eshghi, F., Bakhshimoghaddam, F., Rasmi, Y., & Alizadeh, M. (2019). Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial. Clinical Nutrition Research, 8(4), 318–328. https://doi.org/10.7762/cnr.2019.8.4.318
  14. Hidayati, D. R., Yuliati, Y., & Pratiwi, K. R. (2017). Hubungan asupan lemak dengan kadar trigliserida dan indeks massa tubuh sivitas akademika uny. Jurnal Prodi Biologi, 6(1), 25–33. http://journal.student.uny.ac.id/ojs/index.php/biologi/article/view/6055
  15. Jariyah, Yektiningsih, E., & Sarofa, U. (2019). Evaluation of antidiabetic and anticholesterol properties of biscuit product with mangrove fruit flour (MFF) substitution. Carpathian Journal of Food Science and Technology, 11(4), 141–152. https://doi.org/10.34302/2019.11.4.13
  16. Jia, Q. fang, Yang, H. xue, Zhuang, N. nan, Yin, X. yuan, Zhu, Z. hua, Yuan, Y., Yin, X. li, Wang, Y., Cheung, E. F. C., Chan, R. C. K., & Hui, L. (2020). The role of lipoprotein profile in depression and cognitive performance: a network analysis. Scientific Reports, 10(1), 1–7. https://doi.org/10.1038/s41598-020-77782-9
  17. Maki, K. C., Pelkman, C. L., Finocchiaro, E. T., Kelley, K. M., Lawless, A. L., Schild, A. L., & Rains, T. M. (2012). Resistant starch from high-amylose maize increases insulin sensitivity in overweight and obese men. Journal of Nutrition, 142(4), 717–723. https://doi.org/10.3945/jn.111.152975
  18. Malindi, T. (2021). Studies In The Application Pf Green Banana Flour Composite From 10 Banana Cultivars In Gluten-Sugar_Free Banana Flour Based Biscuit. https://doi.org/https://hdl.handle.net/10500/28340
  19. Merćep, I., Strikić, D., Slišković, A. M., & Reiner, Ž. (2022). New Therapeutic Approaches in Treatment of Dyslipidaemia—A Narrative Review. Pharmaceuticals, 15(7), 1–13. https://doi.org/10.3390/ph15070839
  20. Nadia, F.S Wati, D.A, Isnawati, M Afifah, D. N. (2020). The effect of processed Tempeh Gembus to triglycerides levels and insulin. Food Research, 4 (4)(August), 1000–1010. https://doi.org/doi.org/10.26656/fr.2017.4(4).415
  21. Park, J., Sung, S. C., Choi, A. H., Kang, H. K., Myeong, J. Y., Suganami, T., Ogawa, Y., & Jae, B. K. (2006). Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals. Diabetes, 55(11), 2939–2949. https://doi.org/10.2337/db05-1570
  22. Pertanian, B. L. (2013). Yoghurt Sinbiotik - Minuman Fungsional Kaya Serat Berbasis Tepung Pisang. Badan Litbang Pertanian, 43(3515), 1–8. https://doi.org/https://123dok.com/document/zle2mloq-yoghurt-sinbiotik-minuman-fungsional-serat-berbasis-tepung-pisang.html
  23. Putri, S. R., & A, D. I. (2015). Obesitas sebagai Faktor Resiko Peningkatan Kadar Trigliserida. Jurnal Majority, 4(9), 78–82. https://juke.kedokteran.unila.ac.id/index.php/majority/article/viewFile/1413/1256.
  24. Rosalina, Y., Susanti, L., Silsia, D., & Setiawan, R. (2018). Characteristics of Banana Flour from Bengkulu Local Banana Varieties. Industria: Jurnal Teknologi Dan Manajemen Agroindustri, 7(3), 153–160. https://doi.org/10.21776/ub.industria.2018.007.03.3
  25. Rosulva, I., Hariyadi, P., Budijanto, S., & Sitanggang, A. B. (2022). Potensi buah mangrove sebagai sumber pangan alternatif potential of mangrove fruit as an alternative food source. Jurnal Teknologi Hasil Pertanian, 14(2), 131–150. https://doi.org/10.20961/jthp.v14i2.55509
  26. Sah, S. P., Singh, B., Choudhary, S., & Kumar, A. (2016). Animal models of insulin resistance: A review. Pharmacological Reports, 68(6), 1165–1177. https://doi.org/10.1016/j.pharep.2016.07.010
  27. Samuel, Varman T.; Shulman, G. I. (2012). Integrating mechanisms for insulin resistance. Cell, 148(5), 852–871. https://doi.org/10.1016/j.cell.2012.02.017.Integrating
  28. Santoso, A. (2011). Serat Pangan (Dietetary Fiber) Dan Manfaat Bagi Kesehatan. In Aslib Proceedings (pp. 35–40). https://doi.org/10.1108/eb050265
  29. Schoeler, M., & Caesar, R. (2019). Dietary lipids, gut microbiota and lipid metabolism. Reviews in Endocrine and Metabolic Disorders, 20(4), 461–472. https://doi.org/10.1007/s11154-019-09512-0
  30. Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., Hayes, L. D., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: A review. Journal of the International Society of Sports Nutrition, 15(1), 1–14. https://doi.org/10.1186/s12970-018-0218-y
  31. Tchernof, A., & Després, J. P. (2013). Pathophysiology of human visceral obesity: An update. Physiological Reviews, 93(1), 359–404. https://doi.org/10.1152/physrev.00033.2011
  32. Winarsi, H., Wijayanti, S. P. M., & Purwanto, A. (2011). Profil Lipid, Peroksidasi Lipid, dan Status Inflamatif Wanita Penderita Sindrom Metabolik Lipid Profile, Peroxide Lipid, and Inflammatory Status in Metabolic Syndrome Woman. 2(5), 1–6. https://doi.org/DOI: http://dx.doi.org/10.21109/kesmas.v5i5.129.
  33. Wulandari, D. L., Putriningtyas, N. D., & Wahyuningsih, S. (2020). Potensi Yogurt Kacang Merah terhadap Kadar Kolesterol HDL pada Remaja Obesitas (Studi Dilakukan pada Mahasiswa Gizi Universitas Respati Yogyakarta). Sport and Nutrition Journal, 2(1), 10–16. https://doi.org/10.15294/spnj.v2i1.38452
  34. Yoon, H., Shaw, J. L., Haigis, M. C., & Greka, A. (2021). Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity. Molecular Cell, 81(18), 3708–3730. https://doi.org/10.1016/j.molcel.2021.08.027
  35. Yuan, G., Al-Shali, K. Z., & Hegele, R. A. (2007). Hypertriglyceridemia: Its etiology, effects and treatment. CMAJ. Canadian Medical Association Journal, 176(8), 1113–1120. https://doi.org/10.1503/cmaj.060963

Open Access Copyright (c) 2024 Masdayani Junita Napitupulu, Ahmad Syauqy, Nyoman Suci Widyastiti, Diana Nur Afifah, Etika Ratna Noer
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