Correlation vitamin D deficiency with obesity and impaired glucose metabolism in women with polycystic ovary syndrome

Achmad Zulfa Juniarto* -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
Siti Zahra Ni'mah -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, and RSIA Kasih Ibu Tegal, Central Java, Indonesia
Ahmad Syauqy -  Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Indonesia
DOI : 10.30867/action.v9i2.1780

Supp. File(s): Research Instrument Research Instrument Research Instrument Ethical Approval

Vitamin D deficiency is a worldwide problem, particularly in Indonesia. Obesity and impaired glucose metabolism have an impact on vitamin D status in women with polycystic ovarium syndrome and are still controversial.  This study aimed  to examine vitamin D levels and the correlation between obesity and impaired glucose metabolism in PCOS patients. This research employed analytical observational techniques with a case-control approach with 40 women diagnosed with Rotterdam Criteria PCOS in Mother and Child Hospital Kasih Ibu Tegal during September-October 2023. This study used the Chemiluminescent Mikropartikel Immunoassay (CMIA) method to measure vitamin D levels in the laboratory. The statistical test utilized were Shapiro-Wilk, Paired T-Test and Mann Whitney and Chi Square. Results: There was no significant difference in the serum 25(OH)D levels between women with PCOS and controls (p>0,05; p=0,745). The group of patients with an obese waist circumference was 9.75 times more likely to develop PCOS than the group with a normal waist circumference (OR = 9,75; 95% CI = 1,16-82,11; p = 0,013). In conclusion, there was no substantial variation in vitamin D levels between PCOS and non-PCOS patients. Vitamin D deficiency correlates with obesity but does not correlate with impaired glucose metabolism.

 

Supplement Files

Keywords : Vitamin D, Polycystic Ovary Syndrome, Obesity,Impaired glucose Metabolism

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Open Access Copyright (c) 2024 Achmad Zulfa Juniarto, Siti Zahra Ni'mah, Ahmad Syauqy
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AcTion: Aceh Nutrition Journal
Published by: Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health.
Soekarno-Hatta Street, No. 168. Health Polytechnic of Aceh, Aceh Besar, 23352. Telp/Fax: 0651 46126 / 0651 46121.
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