Effect of ginger kombucha consumption on blood pressure in patients with essential hypertension
Essential hypertension remains a major global public health problem that requires effective non-pharmacological management strategies. Fermented functional beverages rich in antioxidants, such as ginger kombucha, have been proposed as potential complementary interventions for blood-pressure control. This study aimed to evaluate the effects of ginger kombucha consumption on blood pressure in patients with essential hypertension. A quasi-experimental pretest–posttest control group design was conducted involving 62 patients with hypertension at Medan Adventist Hospital, Indonesia, in April 2025. Participants were allocated to an intervention group (n = 31), which consumed 200 mL ginger kombucha twice daily for 14 days, and a control group (n = 31), which received no intervention. Blood pressure was measured using a standardized digital sphygmomanometer. Data were analyzed using paired and independent t-tests. The intervention group demonstrated a significant reduction in both systolic and diastolic blood pressure, with mean decreases of 16.2 mmHg and 10.1 mmHg, respectively (p < 0.001), whereas the changes in the control group were not statistically significant. Between-group comparisons showed significantly greater reductions in blood pressure in the intervention group (p < 0.05), indicating a clinically meaningful effect over a short period. In conclusion, ginger kombucha consumption significantly reduced blood pressure in patients with essential hypertension and may serve as a complementary non-pharmacological strategy for hypertension management. Ethical approval was obtained prior to data collection, and all the participants provided written informed consent.
Keywords : Blood pressure, fermented beverages, hypertension, kombucha, ginger (Zingiber officinale)
- Anantachoke, N., Duangrat, R., Sutthiphatkul, T., Ochaikul, D., & Mangmool, S. (2023). Kombucha Beverages Produced from Fruits, Vegetables, and Plants: A Review on Their Pharmacological Activities and Health Benefits. Foods, 12(9), 1818. https://doi.org/10.3390/foods12091818
- Annisa, A. savira, Khairani, K., & Nurhasanah, N. (2024). Nursing Care for the Elderly with Hypertension. Indonesian Journal of Health Science, 4(6), 640–646. https://doi.org/10.54957/ijhs.v4i6.1083
- Asseggaf, S. N. Y. R. S., Zakiah, M., Ulfah, R., & Putri, T. H. (2024). Blood Pressure Control Education Program, How to Properly Use Antihypertensive Medications and Self-Management for Prolanis Participants with Interactive Lectures at the Kampung Dalam Community Health Center. Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM), 7(8), 3641–3652. https://doi.org/10.33024/jkpm.v7i8.15770
- Bellassoued, K., Ghrab, F., Makni-Ayadi, F., Pelt, J. Van, Elfeki, A., & Ammar, E. (2015). Protective Effect of Kombucha on Rats Fed a Hypercholesterolemic Diet is Mediated by Its Antioxidant Activity. Pharmaceutical Biology, 53(11), 1699–1709. https://doi.org/10.3109/13880209.2014.1001408
- Bulto, L. N., Roseleur, J., Noonan, S., Pinero de Plaza, M. A., Champion, S., Dafny, H. A., Pearson, V., Nesbitt, K., Gebremichael, L. G., Beleigoli, A., Gulyani, A., Schultz, T., Hines, S., Clark, R. A., & Hendriks, J. M. (2024). Effectiveness of Nurse-Led Interventions Versus Usual Care to Manage Hypertension and Lifestyle Behaviour: a Systematic Review and Meta-Analysis. European Journal of Cardiovascular Nursing, 23(1), 21–32. https://doi.org/10.1093/eurjcn/zvad040
- Cardoso, R. B., Caldas, C. P., Brandão, M. A. G., Souza, P. A. de, & Santana, R. F. (2022). Healthy Aging Promotion Model Referenced in Nola Pender’s Theory. Revista Brasileira de Enfermagem, 75(1). https://doi.org/10.1590/0034-7167-2020-0373
- Chou, Y.-C., Lin, H.-W., Wang, C.-Y., Hsieh, C.-C., Santoso, S. P., Lin, S.-P., & Cheng, K.-C. (2024). Enhancing Antioxidant Benefits of Kombucha Through Optimized Glucuronic Acid by Selected Symbiotic Fermentation Culture. Antioxidants, 13(11), 1323. https://doi.org/10.3390/antiox13111323
- Ekayanti, E., & Nurfitriani, D. (2025). Comparison of Starfruit Extract (Averrhoa Bilimbi L) and Ginger Extract (Singiber Officianale Rosc) on Reducing Blood Pressure in Pregnant Women at the Tanti Kirana Main Clinic in Rangkasbitung. MAHESA : Malahayati Health Student Journal, 5(2), 534–541. https://doi.org/10.33024/mahesa.v5i2.16646
- Elkhtab, E., El-Alfy, M., Shenana, M., Mohamed, A., & Yousef, A. E. (2017). New Potentially Antihypertensive Peptides Liberated in Milk During Fermentation with Selected Lactic Acid Bacteria and Kombucha Cultures. Journal of Dairy Science, 100(12), 9508–9520. https://doi.org/10.3168/jds.2017-13150
- Febianti, Z., Wahyudi, M. S. S., & Abrori, C. (2022). Factors Associated with Hypertension: A Cross-sectional Study in the Rural Area of Klakah, Lumajang, East Java. Jurnal Kesmas Untika Luwuk : Public Health Journal, 13(1), 12–19. https://doi.org/10.51888/phj.v13i1.102
- Fraiz, G. M., Costa, M. A. C., Cardoso, R. R., Hébert, J. R., Zhao, L., Corich, V., Giacomini, A., Milagro, F. I., Barros, F. A. R., & Bressan, J. (2024). Black Tea Kombucha Consumption: Effect on Cardiometabolic Parameters and Diet Quality of Individuals with and without Obesity. Fermentation, 10(8), 384. https://doi.org/10.3390/fermentation10080384
- Ghayur, M. N., Gilani, A. H., Afridi, M. B., & Houghton, P. J. (2005). Cardiovascular Effects of Ginger Aqueous Extract and its Phenolic Constituents are Mediated Through Multiple Pathways. Vascular Pharmacology, 43(4), 234–241. https://doi.org/10.1016/j.vph.2005.07.003
- Harahap, U., Syahputra, R. A., Ahmed, A., Nasution, A., Wisely, W., Sirait, M. L., Dalimunthe, A., Zainalabidin, S., Taslim, N. A., Nurkolis, F., & Kim, B. (2024). Current insights and future perspectives of flavonoids: A promising antihypertensive approach. Phytotherapy Research, 38(6), 3146–3168. https://doi.org/10.1002/ptr.8199
- Hasani, H., Arab, A., Hadi, A., Pourmasoumi, M., Ghavami, A., & Miraghajani, M. (2019). Does Ginger Supplementation Lower Blood Pressure? A Systematic Review and Meta‐Analysis of Clinical Trials. Phytotherapy Research, 33(6), 1639–1647. https://doi.org/10.1002/ptr.6362
- Indriawati, R., & Usman, S. (2018). Community Empowerment as an Effort for Early Detection of Hypertension Risk Factors. Jurnal Surya Masyarakat, 1(1), 59. https://doi.org/10.26714/jsm.1.1.2018.59-63
- Khamidah, A.-, & Antarlina, S. S. (2020). Kombucha Drink Opportunities as Functional Food. Agrika, 14(2), 184. https://doi.org/10.31328/ja.v14i2.1753
- Kristinawati, B., Latiifah, I. R. N., Anata, D. S., Pratama, R. A., & Rahayu, S. (2023). Improving Family Cadre Knowledge on the Use of Medicinal Plants for Hypertension Sufferers through Health Education. JMM (Jurnal Masyarakat Mandiri), 7(2), 1362. https://doi.org/10.31764/jmm.v7i2.13561
- Mahardani, O. T., & Yuanita, L. (2021). Effects of Processing and Storage Methods on Phenolic Compound Content and Antioxidant Activity. Unesa Journal of Chemistry, 10(1), 64–78. https://doi.org/10.26740/ujc.v10n1.p64-78
- Mao, Q.-Q., Xu, X.-Y., Cao, S.-Y., Gan, R.-Y., Corke, H., Beta, T., & Li, H.-B. (2019). Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods, 8(6), 185. https://doi.org/10.3390/foods8060185
- Maryati, Y., Susilowati, A., Artanti, N., Lotulung, P. D. N., & Aspiyanto, A. (2020). The Effect of Fermentation Time on Antioxidant Activity and Betacyanin Content of Functional Drinks from Dragon Fruit (Hylocereus Polyrhizus) and Beetroot (Beta Vulgaris). Jurnal Bioteknologi & Biosains Indonesia (JBBI), 7(1). https://doi.org/10.29122/jbbi.v7i1.3732
- Niu, Y., Chen, X., Xiao, L., Li, W., Feng, L., & Aierken, A. (2025). The Relationship between Dietary Flavonoid Intake and Hypertension: a Cross-Sectional Study from NHANES. Frontiers in Cardiovascular Medicine, 12. https://doi.org/10.3389/fcvm.2025.1518549
- Pandit, B. T. S., Ariikah, D. L., Mahendra, E. S., Rakha, A. M., Irien, E. H., Hanang, A. A., Rachmat, A. P., & Yudi, H. O. (2023). Diagnosis and Non-pharmacological Therapy of Hypertension. Cermin Dunia Kedokteran, 50(6), 322–330. https://doi.org/10.55175/cdk.v50i6.624
- Pramono, A., Gunawan, W. Ben, Nurkolis, F., Alisaputra, D., Limen, G. A., Alfaqih, M. S., & Ardiaria, M. (2024). Free Radical Scavenging, α-Amylase, α-Glucosidase, and Lipase Inhibitory Activities of Metabolites from Strawberry Kombucha: Molecular Docking and in Vitro Studies. Pharmacia, 71, 1–12. https://doi.org/10.3897/pharmacia.71.e116794
- Rezaldi, F., Fadillah, M. F., Mu’jijah, M., Abdilah, N. A., & Meliyawati, M. (2022). The Potential of Butterfly Pea Kombucha as an Appeal to Carita Beach Tourists in Increasing Immunity. SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan, 6(2), 867. https://doi.org/10.31764/jpmb.v6i2.8472
- Rosa, A. C., Corsi, D., Cavi, N., Bruni, N., & Dosio, F. (2021). Superoxide Dismutase Administration: A Review of Proposed Human Uses. Molecules, 26(7), 1844. https://doi.org/10.3390/molecules26071844
- Santos, M. G. dos, Pleutim, N. I., Queiroz-Cardoso, A. I. de, Ramalho, L. dos S., Souza, V. S. de, & Teston, E. F. (2025). Use of the Health Promotion Model by Nursing in Primary Care: an integrative review. Revista Brasileira de Enfermagem, 78(2). https://doi.org/10.1590/0034-7167-2024-0096
- Sari, N. N., & Suharyanto, S. (2020). The Effect of Fermentation Time on Total Flavonoid Content in Jackfruit Seed Tape Extract (Artocarpus heterophylla Lamk.). Jurnal Kesehatan Kusuma Husada, 53–61. https://doi.org/10.34035/jk.v12i1.552
- Suratih, K., & Cahyanto, E. B. (2023). Mosque-Based Non-Communicable Disease (NCD) Prevention Program in Gumpang Village, Kartasura. Jurnal KESPERA, 2(2), 56. https://doi.org/10.34310/jkspr.v2i2.786
- Wanyo, P., Chamsai, T., Toontom, N., Nghiep, L. K., & Tudpor, K. (2025). Evaluation of In Vitro Digested Mulberry Leaf Tea Kombucha: A Functional Fermented Beverage with Antioxidant, Anti-Inflammatory, Antihyperglycemic, and Antihypertensive Potentials. Fermentation, 11(5), 258. https://doi.org/10.3390/fermentation11050258
- Zubaidah, E., Fibrianto, K., & Kartikaputri, S. D. (2021). The Potential of Kombucha Tea Leaves (Camellia sinensis) and Robusta Coffee Leaves (Coffea robusta) as Probiotic Drinks. Jurnal Bioteknologi & Biosains Indonesia (JBBI), 8(2). https://doi.org/10.29122/jbbi.v8i2.4186
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