Abstract
Background: Filariasis is a disease caused by parasitic nematodes of Filariae. Filariasis is caused by filarial worm species, namely Wuchereria bancrofti, Brugia malayi, and Brugia timori. This disease is transmitted through the bite of infected mosquitoes (Anopheles, Aedes, and Culex). Symptoms of filariasis in men or women include damage to the lymphatic system swelling of the arms, legs, and genitals, which causes pain, decreased productivity, and social problems. Filarial diagnosis through examination of blood smears to detect filarial parasites in the blood, accompanied by hematological and clinical chemical examinations
Objective: This study aimed to describe filariasis through blood tests (blood smears, hematological examinations, and clinical chemistry examinations) on filariasis respondents using a cross-sectional approach.
Method: This type of descriptive research uses a cross-sectional approach. The research subjects were 6 filarial respondents in Pedurungan District, Semarang City. The examination was conducted at the Tologosari Wetan and Kulon Health Centers on September 12-18, 2020. Secondary data collection was obtained from capillary blood examination using thin blood smears, automatic hematological examination using a hematology analyzer, and clinical chemistry examination using the spectrophotometer method with a spectrophotometer. The research data was processed and analyzed using Univariate analysis using maximum, minimum, and average values.
Results: Hematological examination for hemoglobin level of 12,5 g%, leukocytes 3200 cells/ml, platelets 137.00 cells, erythrocytes 4,07x106 cells, lymphocytes 35 cells, neutrophils 73 cells, eosinophils 1 cell, monocytes 9 cells, MCH 30,78 pg, MCV 86,48 fl, MCHC 36,24 g/l and clinical chemistry examination results for cholesterol 145,7 g/dl and triglycerides 104,6 g/dl. Meanwhile, on examination of thin blood smears, microfilariae were found.
Conclusion: The results of the blood smear evaluation showed an abnormality in the size of the red blood cells in the form of microcytic (smaller red blood cell size), and filarial findings were found. In contrast, hematology and clinical chemistry examination results obtained normal results.
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Abdul Halim, A. F. N., Ahmad, D., Miaw Yn, J. L., Masdor, N. A., Ramly, N., Othman, R., Kandayah, T., Hassan, M. R., & Dapari, R. (2022). Factors Associated with the Acceptability of Mass Drug Administration for Filariasis: A Systematic Review. International Journal of Environmental Research and Public Health, 19(19). https://doi.org/10.3390/ijerph191912971
Bohara, S., Tripathi, N., Das, R., Jha, M., & Gupta, V. (2018). The Role of Haematological Parameters in Predicting Filariasis with Special Emphasis on Absolute Eosinophil Count: A single Institutional Experience. Journal of Dental and Medical Science, 17(11), 24–27. https://doi.org/10.9790/0853-1711032427
Dinkes Provinsi Jateng. (2017). Media Informasi Kesehatan. 37, 1–40.
Dinkes Provinsi Jateng. (2019). Profil Kesehatan Provinsi Jawa Tengah Tahun 2018 (Health Profile of Central Java Province in 2018). DInas Kesehatan Provinsi Jateng.
Fitriyana, Dyah, M., & Rudatin, W. (2018). Distribusi Spasial Vektor Potensial Filariasis dan Habitatnya di Daerah Endemis. HIGEIA (Journal of Public Health Research and Development), 2(2), 320–330. https://doi.org/10.15294/higeia.v2i2.17851
Gordon, C. A., Jones, M. K., & McManus, D. P. (2018). The History of Bancroftian lymphatic Filariasis in Australasia and Oceania: Is There a Threat of Re-occurrence in Mainland Australia? Tropical Medicine and Infectious Disease, 3(2). https://doi.org/10.3390/tropicalmed3020058
Hossain, M., Yoshimura, K., Akter, S., Hoque, A., & Afrin, S. (2020). A Study on Fillaria Patients Attended Filaria and General Hospital in Bangladesh. Microbiology & Infectious Diseases, 4(2), 1–5. https://doi.org/10.33425/2639-9458.1082
Infodatin Kemenkes. (2018). Menuju Indonesia Bebas Filariasis. Kementerian Kesehatan RI.
Iswanto, F., Emmy, R., & Syamsulhuda, B. (2017). Faktor – Faktor Yang Berhubungan Dengan Perilaku Pencegahaan Penyakit Filariasis Pada Masyarakat Di Kecamatan Bonang
Kabupaten Demak. Jurnal Kesehatan Masyarakat (e-Journal), 5(5), 990–999.
Jacob, E. A. (2016). Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. American Journal of Laboratory Medicine, 1(3), 34–57. https://doi.org/10.11648/j.ajlm.20160103.12
Joseph, H. (2012). Laboratory Diagnosis of Lymphatic Filariasis in Australia : Available Laboratory Diagnosis Tools and Intrepetation. Australian Journal of Medical Science, 33(May), 4–45.
Kanaan Al-Tameemi, & Kaabakli, R. (2019). Lymphatic Filariasis: an Overview. Asian Journal of Pharmaceutical and Clinical Research, 12(12), 1–5. https://doi.org/10.22159/ajpcr.2019.v12i12.35646
Kementerian Kesehatan RI. (2014). Permenkes RI No 94 Tentang Penanggulangan Filariasis.
Kementerian Kesehatan RI. (2017). Peraturan Menteri Kesehatan RI No 27 Tahun 2017 Tentang Pedoman Pencegahan Dan Pengendalian Infeksi Di Fasilitas Pelayanan Kesehatan. In Peraturan Menteri Kesehatan Republik Indonesia Nomor 27 Tahun 2017 T (Issue 857, p. 857).
Kementerian Kesehatan RI. (2019). Situasi Filariasis di Indonesia. In Infodatin Pusat Data dan Informasi Kementerian Kesehatan RI.
Kerketta, L. S., & Ghosh, K. (2018). Circulating microfilariae in haematological malignancies: Do they have a role in pathogenesis? Journal of Helminthology, 92(1), 125–127. https://doi.org/10.1017/S0022149X17000062
Mathison, B. A., Couturier, M. R., & Pritt, B. S. (2019). Diagnostic identification and differentiation of microfilariae. Journal of Clinical Microbiology, 57(10). https://doi.org/10.1128/JCM.00706-19
Musso, D. (2013). Relevance of the eosinophil blood count in bancroftian filariasis as a screening tool for the treatment. Pathogens and Global Health, 107(2), 96–102. https://doi.org/10.1179/2047773213Y.0000000083
Pengurus Besar Ikatan Dokter Indonesia. (2014). Panduan Praktik Klinis Bagi Dokter Di Faslitas Pelayanan Kesehatan Primer. In Ikatan Dokter Indonesia (Revisi).
Perkeni. (2019). Pedoman Pengelolaan Dislipidemi di Indonesia 2019 (Guidelines for Dyslipidemia Management in Indonesia 2019). In Pb Perkeni. https://doi.org/10.1002/bit.22430
Saeed, M., Al-Shammari, E. M., Khan, S., Alam, M. J., & Adnan, M. (2016). Monitoring and Evaluation of Lymphatic Filariasis interventions: Current Trends for Diagnosis. Reviews and Research in Medical Microbiology, 27(2), 75–83. https://doi.org/10.1097/MRM.0000000000000063
Sarojiji S, Senthilkumaar P. (2013). Haemotological Studies of Lymphatic Filariasis Wuchereria bancrofti Affected Patiens in Arrakonam Area, Tamil Nadu, India. European Journal of Experimental Biology, 3(2), 194–200.
Shagana, J. A. (2014). Diagnostic cells in the peripheral blood smear. Journal of Pharmaceutical Sciences and Research, 6(4), 213–216.
Syed, A. (2019). ‘ A review of Filariasis .’ International Journal of Current Research in Medical Science, 5(2), 26–30.
Watu, E., Supargiyono, & Haryani. (2020). The Effect of Lymphoedema Exercises and Foot Elevation on the Quality of Life of Patients with Elephantiasis. Journal of Tropical Medicine, 2020, 1–7. https://doi.org/10.1155/2020/6309630
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